combination of treatments will be needed to reach a satisfactory result. Moreover, in clinical practice it is not always possible to definitively differentiate between subtype 1 and subtype 2 rosacea. Indeed, people may have more signs and symptoms of subtype 1 at a point in time and at another point in time more features its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: Confidence interval GRADE Working Group Koçak 2002, Nielsen 1983a 4Bjerke 1989, Breneman 1998, Nielsen 1983a 5 Although for two studies the sequence one study participants switched to the other treatment arm if they failed to respond to the allocated treatment, and one study was designed as a superiority trial but reported as a non‐inferiority trial. See: Summary of findings for quality: Further research is very unlikely to change our confidence in the estimate of effect. Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely 75% versus 66% of participants (Monk 1991), "the reduction of papules and pustules was the same in both groups" (Nielsen 1983b), decrease of 68% versus 77% in papule count and of 53% and 61% in pustule count (Schachter 1991). In Veien 1986 only medians were provided

risk Placebo Metronidazole HRQOL ‐ not measured See

scale 0 to 4). Scale from: 0 to 4. The mean assessment of erythema or telangiectasia in the control group was ‐4 on CEA The mean assessment of erythema or telangiectasia in the intervention group was 1.00 higher (0.18 lower to 2.18 higher) 60 (1 study1) ⊕⊕⊝⊝ Shibboleth Search for your institution's name below to login via Shibboleth Search for your institution's name below to login via Shibboleth Search for your institution's name below to login via Shibboleth Search for your institution's name below to login via Shibboleth Search for your institution's name below to login via Shibboleth Search for your institution's name Medical Academy dan Dip. Aesthetic Medicine from USA, dan boleh bertutur dengan pesakit dalam bahasa Kantonis, Inggeris, Hokkien, Melayu, Mandarin. Trafik below to login via Shibboleth Search for your institution's name below to login via was originally effective for treatment of infections caused by this micro‐organism Body dysmorphic disorder An anxiety disorder surrounding perceived flaws in one's own appearance Cytokines A small protein released by cells, and having a specific effect on the behavior in this fashion. follow‐up mail that allocation concealment is not yet satisfactorily answered 9‐8: sent again, no reply Ertl 1994 Yes No Dr Levine, study 17 years old, no further data available Fabi 2011 No No sfabi@gbkderm.com 2‐8‐2014 (sequence generation and allocation concealment and dropouts?) Follow‐up mail 11‐8‐2014 and 17‐8‐2014, no reply Fowler 2007 Yes Yes fowlerjoe@msn.com and christian.loesche@galderma.com. "Randomisation in human hair follicles Down‐regulation Process of reducing or suppressing a response to a stimulus Epidermal barrier The skin's front line of defence in the upper layer of the skin (the epidermis) against environmental factors such as UV light, chemicals, bacteria and other organisms and limits water loss from the body Innate the estimate. Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. Very low quality: We are very uncertain about the estimate. 1Chang 2012 2 Downgraded one level due to serious imprecision (low sample size, optimal sample size is not met) 3 Downgraded one Search for your institution's name below to login via Shibboleth Search for your institution's name below to login via Shibboleth Search for your institution's name below to login via Shibboleth Search for your institution's name below to login via Shibboleth Search for your institution's name below to login via Shibboleth Search for your institution's name below to login via Poster, very limited data reported, PI failed to respond to several e‐mails Guillet 1999 Metronidazole 75% gel versus metronidazole 0.75% lotion 114 Poster, very limited data reported, old study, not able to contact PI Huang 2014 Doxycycline 40 mg versus placebo 170 Poster abstract, limited data, unclear how many were randomised to each group, PI failed to respond to several years; there were more women (8332) than men (3718) and the gender was unreported for 1581 1998, Koçak 2002,Nielsen 1983a 7 Downgraded one level due to serious imprecision (small confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: Confidence interval GRADE Working Group grades of evidence High quality: Further research is very unlikely to change our confidence in the estimate of effect. Moderate quality: Further research comment Not estimable ‐ See comment No study addressed this outcome Duration of remission ‐ not measured See comment See comment Not estimable ‐ See comment No study addressed this outcome *The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk Kulat. Naqi Naj Sebagai seorang lelaki, saya akan mengatakan ini adalah klinik terbaik untuk wajah. Saya cadangkan untuk orang yang mencari pakar penjagaan kulit. Inilah klinik terbaik. Jika komunikasi dengan doktor secara berkesan adalah kebimbangan untuk anda, anda tidak perlu risau kerana Clique Clinic mempunyai pasukan doktor yang boleh bertutur dalam pelbagai bahasa. Antara doktor berkenaan termasuklah: Dengan 7 tahun dalam